Choice is good and all that matters is that each user is happy as you are with your choice.
But the differences ("down sides") are certainly more than setup time, among the common reasons some prefer full-size over pop-ups ....
+ ability to access the trailer and all it's amenities at any time (e.g. packing in the days before a trip, the 'quick lunch stop' while on the road)
+ no 'setup chores' in hot or wet weather (BTDT in my StarCraft pop-up days and it is not fun)
+ more private inside toilet and shower
+ more storage space/cabinets
+ generally larger refrigerator options
+ better thermal performance/comfort in extreme hot and cold climes
+ better noise insulation (much appreciated in crowded campgrounds)
+ there's more, the longer you RV the more you learn ...
And then there was the time I was forced to stay in a fenced compound at Glacier National Park because 'soft side RVs' were not allowed in the nice RV campground during a 'bad bear season' :-(
There's definite pros and cons for each type, but to oversimplify or ignore them doesn't do anyone any good, just the opposite. Everyone must seriously consider what fits their specific situation best and 'one size/one type' does not fit all.
My opinion was one from experience with a family of 4. If you intend on towing with the Escape, or any 3500lbs tow limit in general, you'll be hard-pressed to find a light travel trailer that fits and sleeps 4 people as comfortable as a popup and also stay at a reasonable tow weight. At this weight class and with 4 (or more) people the popup trailer is the best option for comfort and price.
Your list is a good reference.
However, the ease of setup is better on some popups than others, as you said, you can't generalize.
Keeping food in a cooler that's in the car or stopping off for a bite to eat in the next town is just as ease as pulling over and starting up the cook top to make a fast snack/meal.
Personally, we got a tent trailer without a toilet so we don't have deal with that type of mess. When piping goes bad, ugg, no thanks! I'd rather the space go to something more useful like storage, etc. Most campsites we go to have a washroom/shower, not an issue.
Appliances are sometimes bigger in a travel trailer, no doubt. As an example our 2015 Jayco 1007 UD has a 2 burner cook top that can be moved in or outdoors, a 3way fridge, furnace, hot water tank, we bought a small microwave oven, 2 dinettes that seat 7 comfortably, a double and king bed, sleeps 7 adults comfortably , outside shower and a keyfob remote to raise and lower the roof. New its worth $18,000 CDN. Equivalent space capacity of travel trailer is going to be $30,000+ and way over the Escape's tow limit. An Explorer or larger vehicle would be needed to tow something like that safely.
As far as campsites that don't allow popups or hybrids there are a 100 more in the area that do.
Noise hasn't been an issue, campsites usually state no noise after 10-11pm so its easy to deal with it if it gets excessive.
Heating, we camped in 0 degrees Celsius with our popup earlier this year. The trailer never got cold and we had the thermostat up halfway. Inside, wearing t-shirts, playing Monoploy ;-) We don't even own those bunk-buddies.